Scientific Sense ®

Scientific Sense ® by Gill Eapen: Prof. Julia Lane is a Professor at the NYU Wagner Graduate School of Public Service. She served in the National AI Research Resources task force and also on the advisory committee on data for evidence building. Her book democratizing our data a manifesto was published in 2020 and she was one of the early guests on this podcast. 

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Scientific Sense ® by Gill Eapen: Ayelet Fishbach is Professor of Behavioral Science and Marketing at the University of Chicago Booth School of Business, and the past president of the Society for the Science of Motivation and the International Social Cognition Network (ISCON).  

You think failure is hard? So is learning from it Motivating personal growth by seeking discomfort Social exploration: When people deviate from options explored by others. Surprised elaboration: When White men get longer sentences. Can’t wait or won’t wait? The two barriers to patient decisions The structure of intrinsic motivation  Get it Done: Surprising Lessons from the Science of Motivation.   

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Scientific Sense ® by Gill Eapen: Prof. Holden Thorp is Editor-in-Chief of Science family of journals. Before he was provost at Washington University where he holds appointments in both chemistry and medicine.  https://www.science.org/doi/10.1126/science.abq8460 It ain’t over ’til it’s over   The Biden administration is sheepishly waving a checkered flag on the pandemic.   h

ttps://www.science.org/doi/full/10.1126/science.adf3072 Remember, do no harm? When the advocacy group America’s Frontline Doctors appeared on the steps of the United States Supreme Court in 2020, falsely stating that hydroxychloroquine was a cure for COVID-19, their pronouncement was virally shared by right-wing media and soundly debunked by medical academicians.   

https://www.science.org/doi/10.1126/science.adg2577 Hard, not easy Science’s Breakthrough of the Year is the successful launch and deployment of the James Webb Space Telescope (JWST).  

https://www.science.org/doi/10.1126/science.abo3934 Science needs affirmative action As science struggles to correct systemic racism in the laboratory and throughout academia in the United States, external forces press on, making it even more difficult to achieve equity on all fronts—including among scientists. The latest example is the decision by the US Supreme Court to hear cases brought against Harvard University and the University of North Carolina (UNC) at Chapel Hill challenging their right to use race as a factor in undergraduate admissions.

Scientific Sense ® by Gill Eapen: Prof. Leah Krubitzer is professor in the Department of Psychology and Center for Neuroscience at the University of California, Davis.   Her current research focuses on the impact of early experience on the cortical phenotype, and she specifically examines the effects of the sensory environment on the development of connections, functional organization and behavior and seeks to understand how culture impacts brain development.   

The Combinatorial Creature: Cortical Phenotypes within and across Lifetimes.   

Not all cortical expansions are the same: The coevolution of the neocortex and the dorsal thalamus in mammals  Future of the Brain: Essays by the World’s Leading Neuroscientists  

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Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.  

A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115   “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals  Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021   A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.   A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066  “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc  “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021)  “Looking Beyond DNA to See Cancer with New Clarity,”   Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily.   Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article  Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019).  See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more)   Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed]    Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Scientific Sense ® by Gill Eapen: Alessandro Gavazza is Professor of Economics at the London School of Economics and Research Fellow of the Centre for Economic Policy Research. He is an applied economist, with main interests in industrial organization. His research focuses on the role of frictions in markets.  Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

The Persistent Effects of Decreasing Labor-Market Discrimination, Do Youth Employment Programs Work? Evidence from the New Deal, The association between educational attainment and longevity using individual-level data from the 1940 census, Discrimination and Racial Disparities in Labor Market Outcomes, and The Incentive Effects of Cash Transfers to the Poor  

Scientific Sense ® by Gill Eapen: Adriana Lleras-Muney is a Professor of Economics at UCLA. Her research examines the relationships between socio-economic status and health, with a particular focus on education and income.   Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Deep History and the Rhythm of Catastrophe and Merleau-Ponty and the Eco-Literary Imaginary,   

Scientific Sense ® by Gill Eapen: Prof. Louise Westling is Professor Emerita of English and Environmental Studies at the University of Oregon. Her research focuses on ecophenomenology and literature, animality, and embodiment in language. A related activity is herding sheep with Australian Kelpies, a good way to learn and develop cross-species communication.  

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What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion? Evidence for the Involvement of TNF and NF-kB in Hippocampal Synaptic Plasticity, NF-κB p50 subunit knockout impairs late LTP and alters long term memory in the mouse hippocampus, Early Growth Response 2 (Egr-2) Expression is Triggered by NF-κB Activation, and Chronic dietary creatine enhances hippocampaldependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-κB   

Scientific Sense ® by Gill Eapen: Prof. Benedict C. Albensi is a Professor and Chair of the Department of Pharmaceutical Sciences and the co-director of the BRAIN Center at Nova SouthEastern University. His research interests include factors involved in ageing, cognition, and Alzheimer's disease (AD), such as nuclear factor kappa B (NF-kB), a mediator of inflammation but also a required molecule for memory.   

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WOMEN AND STEM, Race, Ethnicity, and NIH Research Awards, Reflections on race, ethnicity, and NIH research awards, Gender, Race, and Academic Career Outcomes —Does Economics Mirror Other Disciplines?, Does Mentoring Increase the Collaboration Networks of Female Economists? An Evaluation of the CeMENT Randomized Trial, Women in Academic Economics: Have We Made Progress?, and Association of Mask Mandates and COVID-19 Case Rates, Hospitalizations, and Deaths in Kansas  

Scientific Sense ® by Gill Eapen: Prof. Donna Ginther is Professor of Economics and the director of the Institute for Policy and Social Research at the University of Kansas. Her Research Interests include scientific labor markets, gender differences in employment outcomes, wage inequality, scientific entrepreneurship, and children’s educational attainments.   

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Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly, Structural characterization of the zinc binding domain in cytosolic PSD-95 interactor, The Role of PSD-95 and Cypin in Morphological Changes in Dendrites Following Sublethal NMDA Exposure (cypin): Role of zinc binding in guanine deamination and dendrite branching, and Cypin: A novel target for traumatic brain injury.  

Scientific Sense ® by Gill Eapen: Prof. Bonnie Firestein is Professor of Neuroscience at Rutgers University. Her interests include Regulation of dendrite patterning, synaptogenesis, and neural circuitry, with relevance to CNS injury and schizophrenia.   

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Blood and stories: how genomics is rewriting race, medicine and human history, and Replicant Being - Law and Strange Life in the Age of Biotechnology  

Scientific Sense ® by Gill Eapen: Prof. Priscilla Wald is Professor of English and Gender Sexuality and feminist Studies at Duke University,  She works on U.S. literature and culture, contemporary narratives of science and medicine, science fiction literature and film, law, and environmental studies.  

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Towards complete and error-free genome assemblies of all vertebrate species, The Earth BioGenome Project 2020: Starting the clock, and Scientific excellence in sequencing all life on Earth depends on justice, equity, diversity and inclusion  

 Scientific Sense ® by Gill Eapen: Dr. Marcela Uliano-Silva is Senior Bioinformatician at the Wellcome Sanger Institute. Her research interests are (i) mechanisms of genome evolution, (ii) the improvement of genome assembly pipelines and (iii) actions towards inclusion and diversity in science.   

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The hunt for rogue planets just got tougher, No large population of unbound or wide-orbit Jupiter-mass planets, Kepler K2 Campaign 9: I. Candidate short-duration events from the first space-based survey for planetary microlensing,  Kepler K2 Campaign 9: II. First space-based discovery of an exoplanet using microlensing, ExELS: an exoplanet legacy science proposal for the ESA Euclid mission I. Cold exoplanets, and WFIRST and EUCLID: enabling the microlensing parallax measurement from space.  

Scientific Sense ® by Gill Eapen: Dr. Iain McDonald is lecturer in Astrophysics at the Open University and Research Fellow at the University of Manchester. His research interests include exoplanets and dying stars  

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Reinforcing the supply chain of umifenovir and other antiviral drugs with retrosynthetic software,  Ultrahigh-Throughput Experimentation for Information-Rich Chemical Synthesis, A map of the amine–carboxylic acid coupling system, Molecular Sonification for Molecule to Music Information Transfer   

Scientific Sense ® by Gill Eapen: Prof. Timothy Cernak is Assistant Professor of Medicinal Chemistry at the University of Michigan. His Lab studies the interface of chemical synthesis and computer science. 

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COVID mortality in India: National survey data and health facility deaths,  Intergenerational Mobility in India: New Methods and Estimates Across Time, Space, and Communities, The Long-run Development Impacts of Agricultural Productivity Gains: Evidence from Irrigation Canals in India, and Rural Roads and Local Economic Development, and Development Research at High Geographic Resolution: An Analysis of Night Lights, Firms, and Poverty in India using the SHRUG Open Data Platform  

Scientific Sense ® by Gill Eapen: Prof. Paul Novosad is associate professor of economics at Dartmouth College. He examines why poor countries have remained poor for so long, and what policy interventions can help improve people's lives in developing countries.  

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Big Loans to Small Businesses: Predicting Winners and Losers in an Entrepreneurial Lending Experiment, Mental Health Therapy as a Core Strategy for Increasing Human Capital: Evidence from Ghana, Randomization for Causality, Ethnography for Mechanisms: Illiquid Savings for  Liquor in an Autarkic Society, and Pathways out of Extreme Poverty: Tackling Psychosocial and Capital Constraints with a Multi-faceted Social Protection Program in Niger  

Scientific Sense ® by Gill Eapen: Prof. Dean Karlan is Professor of Economics and Finance at Northwestern University, and the Founder and President of Innovations for Poverty Action, a non-profit organization dedicated to discovering and promoting solutions to global poverty problems.  

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Great Philosophical Objections to Artificial Intelligence, The AI Wars, 1950 - 2000, and their consequences, The Role of Consciousness and Artificial Phronēsis in AI Ethical Reasoning, and Robots, Love, and Sex: The Ethics of Building a Love Machine  

Scientific Sense ® by Gill Eapen:  Prof. John Sullins, Professor of Philosophy at Sonoma State University and the director of programming for the Center for Ethics, Law and Society. His specializes in philosophy of technology, philosophical issues of artificial intelligence/robotics, cognitive science, engineering ethics and computer ethics.

The 1991 Reforms and the Quest for Economic Freedom in India, and Battling COVID-19 with dysfunctional federalism: Lessons from India  

Scientific Sense ® by Gill Eapen: Dr. Shruti Rajagopalan is a Senior Research Fellow at the Mercatus Center at George Mason University, and a Fellow at the Classical Liberal Institute at NYU School of Law. Her area of interest is the economic analysis of comparative legal and political systems.   

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SAHRTA: A Supervisory-Based Adaptive Human-Robot Teaming Architecture and Human-Collective Collaborative Site Selection  

Scientific Sense ® by Gill Eapen: Prof. Julie Adams is Professor of Computer Science at Oregon State University. Her research interests include human-machine teaming, and human interaction with unmanned systems.  

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4 Part Series on String Theory : Part 4, Super String Theory  

Scientific Sense ® by Gill Eapen: Prof. Emil Martinec is Professor of Physics at the Enrico Fermi Institute, and the College of the University of Chicago. His research focuses on string theory and particle physics.  

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The origins of the sustainability concept: Risk perception and resource management in early urban centers, Linear Statecraft along the Nile: Landscapes and the Political Phenomenology of Ancient Egypt, and The process of complex societies: dynamic models beyond site-size hierarchies  

Scientific Sense ® by Gill Eapen: Prof. Monica Smith is Professor of Anthropology and the institute of environmental sustainability at UCLA. She is a historian who utilizes archaeological data to analyze the collective effects of routine activities through the study of food, ordinary goods, and architecture.

Early attempts at the Grand Unification Theories in Physics  

Scientific Sense ® by Gill Eapen: Prof. Emil Martinec is Professor of Physics at the Enrico Fermi Institute, and the College of the University of Chicago. His research focuses on string theory and particle physics. 

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4 Part Series on String Theory: Part 2, Theory of Gravity and Quantum Mechanics  

Scientific Sense ® by Gill Eapen: Prof. Emil Martinec is Professor of Physics at the Enrico Fermi Institute, and the College of the University of Chicago. His research focuses on string theory and particle physics.  

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Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex, Neuroimaging Impaired Response Inhibition and Salience Attribution in Human Drug Addiction: A Systematic Review, The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex, and Structural and functional brain recovery in individuals with substance use disorders during abstinence: A review of longitudinal neuroimaging studies  

Scientific Sense ® by Gill Eapen: Prof. Rita Goldstein is the professor of Psychiatry and Neuroscience in the Icahn School of Medicine at Mount Sinai. Her research focuses on neuroimaging and neuropsychological studies in drug addiction.  

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The Bible as a Text of Migration.

Scientific Sense ® by Gill Eapen: Prof. Jacqueline M. Hidalgo is Professor of Latina Studies and of Religion as well as Associate Dean for Institutional Diversity, Equity, and Inclusion at Williams College.   

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Quantitative Easing, Its Aftermath, and Emerging Market Capital Flows, Global Fund Flows and Emerging Market Tail Risk,  Distress Risk in emerging markets, The Macro-prudential stance and the Vulnerability to Global Financial Cycles, Regulatory Forbearance and Zombie Firms, and liberalization of autarkies.  

Scientific Sense ® by Gill Eapen: Prof. Anusha Chari is Professor of Economics at the University of North Carolina, Chapel Hill. Her research is in the fields of macroeconomics, international finance and empirical corporate finance.   

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Evolutionary Change is Naturally Biological and Teleological, Engines of Innovation: Biological Origins of Genome Evolution, What We Have Learned About Evolutionary Genome Change in the Past 7 Decades, What prevents mainstream evolutionists teaching the whole truth about how genomes evolve?, and Evolution, a View from the 21st Century. Fortified.

Scientific Sense ® by Gill Eapen: Prof. James Shapiro is Professor of Microbiology at the University Of Chicago.  An expert in bacterial genetics, he proposes the concept of Natural Genetic Engineering, a process described to account for novelty created in the process of biological evolution. He is an advocate of non-Darwinian evolution and is a critic of the modern synthesis.

Intergenerational effects of early adversity on survival in wild baboons, Social bonds, social status and survival in wild baboons: a tale of two sexes, Better baboon break-ups: collective decision theory of complex social network fissions, Maternal death and offspring fitness in multiple wild primates, Better baboon break-ups: collective decision theory of complex social network fissions, and Glucocorticoid exposure predicts survival in female baboons  

Scientific Sense ® by Gill Eapen: Prof. Susan Alberts is Professor of Biology and chair of the Evolutionary Anthropology department at Duke University. She studies the behavior, ecology, physiology, and genetics of wild populations of large mammals.  

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Pointing gesture in a bird- merely instrumental or a cognitively complex behavior?, Play behaviour, not tool using, relates to brain mass in a sample of birds, Long-Term Attachments and Complex Cognition in Birds and Humans are Linked to Pre-Reproductive Prosociality and Cooperation. Constructing a Hypothesis, and Of Great Apes and Magpies: Initiations into Animal Behaviour   

Scientific Sense ® by Gill Eapen: Prof. Gisela Kaplan is an Emeritus Professor in Animal Behaviour at the University of New England, Armidale, NSW, Australia. Her main research interests are in complex cognition and communication both in birds and primates.  

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Future Directions in Research on Racism-Related Stress and Racial-Ethnic Protective Factors for Black Youth, OC symptoms in African American young adults: The associations between racial discrimination, racial identity, and obsessive-compulsive symptoms, Racism and Health: Challenges and Future Directions in Behavioral and Psychological Research, The Influence of Internalized Racism on the Relationship Between Discrimination and Anxiety,  Racial Identity and Changes in Psychological Distress Using the Multidimensional Model of Racial Identity, The Associations Between Internalized Racism, Racial Identity, and Psychological Distress, Racial residential segregation and economic disparity jointly exacerbate COVID-19 fatality in large American cities, and The Clarion Call of the COVID-19 Pandemic: How Medical Education Can Mitigate Racial and Ethnic Disparities  

Scientific Sense ® by Gill Eapen: Prof. Enrique Neblett is a Professor of Health Behavior and Health Education at the University of Michigan School of Public Health. His research examines the link between racism and health in African American population.  

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Weeding out the Dealers? The Economics of Cannabis Legalization, Cannabis: How to Take Control Back?, Skilled Immigration: A Visa for Growth, Controlling Irregular Migration: Can a Market for Temporary Foreign Work Permits Help?, and Women in Economics: Europe and the World

  Scientific Sense ® by Gill Eapen: Prof. Emmanuelle Auriol is Professor of Economics, Toulouse School of Economics. Her research interests include industrial organization, regulation, labor economy, collective decision making and development economics.   

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Supernova Neutrino Burst Detection with the Deep Underground Neutrino Experiment, A Next-Generation SuperNova Early Warning System for Multi-messenger Astronomy, and COHERENT at the Spallation Neutron Source  

Scientific Sense ® by Gill Eapen: Prof. Kate Scholberg is Professor of Physics at Duke University. Her research interests include experimental elementary particle physics, astrophysics and cosmology.   

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Patterns of island change and persistence offer alternate adaptation pathways for atoll nations, Sustained coral reef growth in the critical wave dissipation zone of a Maldivian atoll, Global-scale changes in the area of atoll islands during the 21st century, The importance of large benthic foraminifera to reef island sediment budget and dynamics at Raine Island, northern Great Barrier Reef, Patterns of Sediment Transport Using Foraminifera Tracers across Sand Aprons on the Great Barrier Reef, Sediment supply dampens the erosive efects of sea level rise on reef islands,  and emergent properties in the responses of tropical corals to recurrent climate extremes  

Scientific Sense ® by Gill Eapen: Dr. Thomas Fellowes is a postdoctoral fellow with the Geocoastal Research Group and the Marine Studies Institute at the University of Sydney. He is working on a project in collaboration with Geoscience Australia exploring the vulnerability of coral reef islands to the threats such as sea-level rise, ocean acidification and increasing storminess.   

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Urban impacts across realms: Making the case for inter-realm monitoring and management, Current and projected global extent of marine built structures, Belowground ecosystem engineers enhance biodiversity and function in a polluted ecosystem, and Linking habitat interactions and biodiversity within seascapes.

Scientific Sense ® by Gill Eapen: Dr Ana Bugnot, Senior Research Associate at the University of Sydney. Her research interests include environmental impact of human development.  

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A coordinated strategy to develop and distribute infographics addressing COVID-19 vaccine hesitancy and misinformation, Addressing Medical Misinformation in the Patient-Clinician Relationship, and Prevalence of Personal Attacks and Sexual Harassment of Physicians on Social Media.  

Scientific Sense ® by Gill Eapen: Prof. Vineet Arora is Professor of Medicine and Dean of Medical Education at the University of Chicago. One of her research interests is the use of social media to improve the workplace learning in teaching hospitals on a variety of topics.  

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Discovering the Biases Children Bring to Language Learning,  Approaching Learning Hands First How Gesture Influences Thought, Taking a Hands-on Approach to Learning, and Using Gesture To Identify and Address Early Concerns About Language and Pragmatics.

Scientific Sense ® by Gill Eapen:  Prof. Susan Goldin-Meadow is Professor of Psychology at the University of Chicago. Her research interests include Language development and creation and Gesture’s role in communicating, thinking, and learning.

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Do Politically Connected Boards Affect Firm Value?, Politically Connected Boards of Directors and The Allocation of Procurement Contracts, Institutional Investors and Corporate Political Activism, and Do credit shocks affect labor demand? Evidence for employment and wages during the financial crisis  

Scientific Sense ® by Gill Eapen: Prof. Jörg Rocholl is the president of ESMT, Berlin. His research interests are in the areas of Corporate Finance, Corporate Governance, and Financial Intermediation.  

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Exposure to Grocery Prices and Inflation Expectations, Behavioral CEOs: The Role of Managerial Overconfidence, Behavioral Corporate Finance: The Life Cycle of a CEO Career, and Investor Experiences and International Capital Flows?

Scientific Sense ® by Gill Eapen: Prof. Ulrike Malmendier is professor of Finance and Economics at the University of California, Berkeley. Her research area of focus is the intersection of economics and finance, and why and how individuals make decision—specifically how individuals make mistakes and systematically  biased decisions  

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The Ethics of Aesthetics: Visualizing Catastrophe and Alphabet Histories  

Scientific Sense ® by Gill Eapen: Prof. Johanna Drucker is Professor of Bibliographical Studies at UCLA. Her research interests span artists’ books, the history of graphic design, typography, experimental poetry, fine art, and digital humanities.   

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Gut microbes contribute to variation in solid organ transplant outcomes in mice, Impact of the Microbiota on Solid Organ Transplant Rejection, Distinct Graft-Specific TCR Avidity Profiles during Acute Rejection and Tolerance, and Resilience of T cell-intrinsic dysfunction in transplantation toleranc  

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Scientific Sense ® by Gill Eapen: Prof. Maria-Luisa Alegre is Professor of Medicine at the University of Chicago. Her laboratory is interested in T cell responses in settings of transplantation, autoimmunity and cancer, with an emphasis on mouse models and emerging extensions onto clinical translation

Scientific Sense ® by Gill Eapen: Prof. Azra Raza is Professor of Medicine and the Director of the MDS Center at Columbia University. Her research focus has been the identification of the presence of cancer as early as possible and to prevent it from developing into its end-stage monstrosity.